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KMID : 0366220050400020111
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Korean Journal of Hematology
2005 Volume.40 No. 2 p.111 ~ p.115
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A Case of Lymphomatoid Papulosis after Allogenic Bone Marrow Transplatation
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Choi Jae-Myoung
Lee Hyun-Woo
Kang Seok-Yun
Jang Jun-Ho
Park Joon-Seong
Choi Jin-Hyuk
Lim Ho-Yeong
Kim Hugh-Chul
Lee Eun-So
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Abstract
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A twenty-year-old man developed pruritic papules on the right forearm on the 25th day after the allogeneic bone marrow transplantation from a HLA-matched related donor. The skin lesion turned out to be lymphomatoid papulosis both histologically and immunophenotypically, not a GVHD skin lesion. Lymphomatoid papulosis is a chronic lymphoproliferative disease of the skin characterized by recurrent crusts of pruritic papules initially appearing on upper trunk and both extremities. The lesions heal spontaneously within 2～8 weeks usually leaving slightly depressed oval scars. Histologically the lesions show wedge-shaped dense dermal infiltrates of lymphoid cells with numerous eosinophils, neutrophils, and atypical lymphocytes. As much as 50% of the infiltrates show atypical lymphocytes and dermal vessels may show endothelial swelling, fibrin deposition, and red blood cell extravasation. We are reporting a case of spontaneously healed CD56+ lymphomatoid papulosis in the patient who received bone marrow transplantation.
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KEYWORD
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GVHD, Lymphomatoid papulosis, Bone marrow transplantation
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